Single Transpulmonary Thermodilution and Continuous Monitoring of Central Venous Oxygen Saturation During Off-pump Coronary Surgery (OPCAB)

Northern State Medical University

Status: Completed

Conditions: Coronary Artery Disease; Hemodynamic Monitoring; Goal Directed Therapy

Treatments: Device: Advanced monitoring; Device: Conventional monitoring

Study type: Interventional

Funder types: Other

Identifiers

NCT00624494

Grant 4347.07.2006 (Other Identifier)

4347.07.2006

Details and patient eligibility

About

The aim of the present study was to evaluate the usefulness of an algorithm based on hemodynamic parameters obtained by single transpulmonary thermodilution (STD) combined with continuous monitoring of central venous oxygen saturation (ScvO2) for perioperative management of patients undergoing OPCAB.

Full description

At the present time, there is an increasing tendency to perform off-pump coronary artery bypass grafting (OPCAB). However, OPCAB poses a variety of challenges from the point of view of the anesthesiologist and the intensivist. The aim of the present study was to evaluate the usefulness of an algorithm based on hemodynamic parameters obtained by single transpulmonary thermodilution (STD) combined with continuous monitoring of central venous oxygen saturation (ScvO2) for perioperative management of patients undergoing OPCAB.

Enrollment: 40 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with coronary artery disease, ranked ASA II-III and scheduled for elective OPCAB

Exclusion criteria

• Age < 18 years
• Severe valve dysfunction or peripheral vascular disease
• Simultaneous interventions (carotid endarterectomy, aneurysm repair, etc.)
• Transfer to CPB during surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Conventional monitoring

Active Comparator group

Description:

hemodynamic monitoring - conventional monitoring

Treatment:

Device: Conventional monitoring

Advanced monitoring

Active Comparator group

Description:

hemodynamic monitoring - advanced monitoring

Treatment:

Device: Advanced monitoring