Sit-to-stand and Peripheral Muscle Strength in COPD

Maugeri Foundation

Status: Completed

Conditions: COPD

Treatments: Other: rehabilitation

Study type: Interventional

Funder types: Other

Identifiers

NCT02487875

Maugeri1

Details and patient eligibility

About

Background: Individuals with COPD may present reduced peripheral muscle strength, which leads to impaired mobility. Comprehensive pulmonary rehabilitation (PR) should include strength training, in particular to lower limbs. Furthermore, simple tools for the assessment of lower extremity muscles' performance are required. Objectives: To assess the muscle strength of COPD patients by the sit-to-stand test (STST) as compared to the one-repetition maximum (1-RM), considered as the gold standard in non-laboratory situations, and to evaluate the responsiveness of STST to a PR program with specific strength training (SPR), compared to usual PR program (UPR). Methods: 60 moderate-to-severe COPD inpatients were randomly included into either the SPR or into the UPR. 30-sec STST, 1-min STST, 1-RM and 6MWT were assessed before and after PRs.

Full description

Background: Individuals with COPD may present reduced peripheral muscle strength, which leads to impaired mobility. Comprehensive pulmonary rehabilitation (PR) should include strength training, in particular to lower limbs. Furthermore, simple tools for the assessment of lower extremity muscles' performance are required. Objectives: To assess the muscle strength of COPD patients by the sit-to-stand test (STST) as compared to the one-repetition maximum (1-RM), considered as the gold standard in non-laboratory situations, and to evaluate the responsiveness of STST to a PR program with specific strength training (SPR), compared to usual PR program (UPR). Methods: 60 moderate-to-severe COPD inpatients were randomly included into either the SPR or into the UPR. 30-sec STST, 1-min STST, 1-RM and 6MWT were assessed before and after PRs.

Enrollment: 60 patients

Sex: All

Ages: 18 to 87 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosis for COPD according to the GOLD criteria.
• no exacerbations over the previous four weeks
• completing PR program
• smoking history ≥10 pack years
• regular treatment with inhaled bronchodilators and inhaled steroids

Exclusion criteria

• any unstable medical condition
• Contraindications for participation in the PR program included musculoskeletal disorders, malignant diseases, unstable cardiac condition, and lack of adherence to the program

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

COPD patients -study group

Experimental group

Description:

COPD inpatients GOLD2-4, in stable conditions,hospitalized to follow a pulmonary rehabilitation programme. The study group performs in addition to the standard programme, also a peripheric muscle strength training

Treatment:

Other: rehabilitation

COPD patients -control group

Active Comparator group

Description:

COPD inpatients GOLD2-4, in stable conditions,hospitalized to follow a pulmonary rehabilitation programme

Treatment:

Other: rehabilitation