Site Preservation After Tooth Extraction

Nanfang Hospital, Southern Medical University

Status: Not yet enrolling

Conditions: Total Absence of Permanent Teeth; Osteogenesis Imperfecta; Tooth Socket

Study type: Observational

Funder types: Other

Identifiers

NCT05258019

NFEC-2021-414

Details and patient eligibility

About

This study is mainly targeted affected teeth which could not be retained, and patients are willing to undergo implant repair at the later stage. After teeth extraction, Geistlich Bio-Oss ® Particles or Bio-Oss ® Collagen are immediately implanted in the teeth extraction socket and covered with Bio-Gide ® collagen membrane for site preservation.Through postoperative follow-up, postoperative clinical and imaging objective indicators, combined with the subjective evaluation of surgeons and patients, and compared with conventional extraction treatment method, the study is aimed to evaluate the effectiveness of different site preservation of alveolar crest preservation, in order to reduce the alveolar bone width and height loss, effectively reduce alveolar bone absorption, or even achieve bone incrementation, thus to get the ideal site preservation effect, to improve the oral implant success rate, improve implant aesthetic score and patient satisfaction, provide more clinical standard reference of the clinical application of site preservation.

Enrollment: 88 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients willing to performed site preservation with Geistlich Bio-Oss ® Particles + Bio-Gide ® collagen membrane after tooth extraction;
• patients willing to performed site preservation with Geistlich Bio-Oss ® Collagen + Bio-Gide ® collagen membrane after tooth extraction;
• patients willing to performed no site preservation after tooth extraction and only conventional healing.

Exclusion criteria

• patients unwilling to sign the informed consent form and the letter of authorization;
• patients has a potential systematic diseases;
• patients had previously been treated with radiation therapy;
• patients can not re-visit on time.

Trial design

88 participants in 3 patient groups

Geistlich Bio-Oss ® Particles + Bio-Gide ® collagen membrane

Description:

The first group of patients selected for site preservation will be performed with Bio-Oss ® Particles + Bio-Gide ® collagen membrane after tooth extraction

Geistlich Bio-Oss ® Collagen + Bio-Gide ® collagen membrane

Description:

The second group of patients selected for site preservation will be performed with Bio-Oss ® Collagen + Bio-Gide ® collagen membrane after tooth extraction

Conventional healing after tooth extraction, without site preservation

Description:

The third group of patients selected will be performed without site preservation after tooth extraction, and only conventional healing