ClinicalTrials.Veeva

Menu

Skeletal and Dental Maturational Stages in a Sample of Egyptian Subjects With Cleft Lip and Palate Deformity

Cairo University (CU) logo

Cairo University (CU)

Status

Unknown

Conditions

Cleft Lip and Palate

Study type

Observational

Funder types

Other

Identifiers

NCT05031039
14422018441165

Details and patient eligibility

About

The aim of this research is to evaluate the skeletal and dental maturation of cleft lip and palate patients in a sample of Egyptian population using the CVM as indicator for the skeletal maturation and the Demirjian method as indicator for the dental one when compared to a group of Egyptian non-CLP subjects of the same age.

Full description

Chronological age (CA) is not considered an accurate method for assessing the stage of physical or growth development of an individual in childhood or adolescence. For that reason, skeletal and dental maturation can be used in order to examine the rate of physical maturation of the population. Cervical vertebral maturation (CVM) method uses lateral cephalometric radiography to evaluate skeletal maturity. It is considered the preferable method due to its advantage of avoiding unnecessary extra radiation. The CVM method developed by Baccetti et al. (2005) depends on the morphology of the three cervical vertebrae (C2, C3, and C4), which divided skeletal growth into six stages of based on the morphology of the previously mentioned cervical vertebrae. The Demirjian method is considered as one of the most worldwide used method for assessment of the dental maturation due to its reliability. It depends on panoramic x-rays through which the dental developmental stage of 7 lower left teeth appears, and according to the gender of the patient the sum of values of the teeth will be transform to age through the standard tables of Carmen M. Nolla; 1960.

Enrollment

250 estimated patients

Sex

All

Ages

6 to 18 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

(1) Subjects with non-syndromic CLP aged 6-18 years. (2) Subjects with no CLP deformity, aged 6-18 years. (4) Patients having complete records comprising dental/medical history and a lateral cephalometric and panoramic radiograph.

(5) No congenitally missing teeth in the mandible. (6) No previous history of trauma to the face, neck.

Exclusion criteria

  • Radiographs of poor quality.
  • Any growth or hereditary or systematic diseases or syndromes
  • Any trauma or fracture of the jaw that might have affected the normal growth of permanent dentition.

Trial design

250 participants in 2 patient groups

Female Egyptian subjects with Cleft Lip and Palate Deformity
Description:
Egyptians females that have unilateral or bilateral cleft lip and palate deformity
Male Egyptian subjects with Cleft Lip and Palate Deformity
Description:
Egyptians males that have unilateral or bilateral cleft lip and palate deformity

Trial contacts and locations

0

Loading...

Central trial contact

omima khaled salah, B.D.S 2014

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems