Skeletal Muscle Parameters of Liver Cirrhosis in Non-invasive Imaging and Outcome (SLIM)

University Hospital Bonn (UKB)

Status: Enrolling

Conditions: Liver Cirrhosis

Treatments: Diagnostic Test: imaging

Study type: Observational

Funder types: Other

Identifiers

NCT03584204

SLIM

Details and patient eligibility

About

The principal aim of this study is to analyse L3-SMI (skeletal muscle index) in a cohort of patients with decompensated liver cirrhosis and TIPS (transjugular intrahepatic portosystemic shunt), and compare the prognostic power with TPMT (transverse psoas muscle thickness). Furthermore, the role of myosteatosis, determined in CT by L3-SMI, MRI and ultrasound will be studied.

Full description

The principal aim of this study is to analyse L3-SMI (skeletal muscle index) in a cohort of patients with decompensated liver cirrhosis and TIPS (transjugular intrahepatic portosystemic shunt), and compare the prognostic power with TPMT (transverse psoas muscle thickness). Furthermore, the role of myosteatosis, determined in CT by L3-SMI, MRI and ultrasound will be studied.

Enrollment: 400 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• liver cirrhosis of any etiology
• CT scan available

Exclusion criteria

• HCC or any malignant disease