Skin Samples of Diabetic Patients and Healthy Volunteers Collection

Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète

Status: Terminated

Conditions: Type 2 Diabetes

Treatments: Other: skin biopsy

Study type: Interventional

Funder types: Other

Identifiers

NCT01349374

2010-A01127-32

Details and patient eligibility

About

The main objective of this study is the Obtention of skin micro-samples collected from healthy volunteers and diabetic patients (type 2 and MODY), intended to be used afterwards to obtain stem cell lines, in the framework of new therapeutic strategies of type 2 diabetes.

Enrollment: 80 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Diabetic patients diagnosed for type 2 diabetes, with a BMI between 20 and 25, without familial history and known genetic cause of diabetes.
• Diabetic patients diagnosed for MODY diabetes (1, 2, 3, 4, 5 or 6), with a BMI between 20 and 25.
• Healthy volunteers, siblings of MODY patients (1, 2, 3, 4, 5 or 6).
• Healthy volunteers without familial history of diabetes.
• Patients over 18 years old.
• Patients with social insurance coverage
• Patients who signed a consent form

Exclusion criteria

• Type 1 diabetic patients.
• Pregnant women or women who might get pregnant

Trial design

80 participants in 4 patient groups

Group1

Experimental group

Description:

healthy volunteers

Treatment:

Other: skin biopsy

group2

Experimental group

Description:

Unaffected siblings of MODY patients

Treatment:

Other: skin biopsy

Group3

Experimental group

Description:

Type2 Diabetic patients

Treatment:

Other: skin biopsy

Group4

Experimental group

Description:

MODY patients

Treatment:

Other: skin biopsy