Skin Sympathetic Nerve Activity and Sympathetic Tone

Kaohsiung Medical University

Status: Invitation-only

Conditions: Healthy; Nerve; Disorder, Sympathetic

Study type: Observational

Funder types: Other

Identifiers

NCT03243448

KMU-DK106011

Details and patient eligibility

About

There are many sympathetic hyperactivity diseases in the investigators' clinical practice. However, the conventional method to measure the sympathetic nerve activity had many limitations such as clinical application, data interpretation and even therapeutic manipulation. Therefore the investigators would like to develop a non-invasive method to record the sympathetic nerve activity in the investigators' study that can help gathering the sympathetic nerve activity easily in the investigators' daily clinical situation. By the determination of sympathetic nerve activity status, the health caregiver can understand the disease more.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 20 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Sympathetic hyperactivity diseases included: hypertension, heart failure atherosclerotic diseases, arrhythmias, cardiomyopathy, pulmonary hypertension, chronic obstructive pulmonary disease, sleep apnea, pulmonary embolism, hepatitis, liver cirrhosis, hepatopulmonary syndrome, hepatorenal syndrome, renal failure, nephritis, irritable bowel syndrome.
• Healthy Volunteers

Exclusion criteria

• Pregnant

Trial design

1,000 participants in 2 patient groups

The general public

Description:

people between 20-85 years old, without sympathetic hyperactivity disease

Sympathetic hyperactivity diseases

Description:

Sympathetic hyperactivity diseases included: hypertension, heart failure atherosclerotic diseases, arrhythmias, cardiomyopathy, pulmonary hypertension, chronic obstructive pulmonary disease, sleep apnea, pulmonary embolism, hepatitis, liver cirrhosis, hepatopulmonary syndrome, hepatorenal syndrome, renal failure, nephritis, irritable bowel syndrome.