Skin Testing and ELISPOT Assay in Patients With a History of Non-Immediate Reactions to Cephalosporins

Chulalongkorn University

Status: Completed

Conditions: Non-immediate Drug Reactions; Cephalosporin Allergy

Treatments: Procedure: Skin tests and ELISPOT assay

Study type: Observational

Funder types: Other

Identifiers

NCT01248377

Chula-ARC 002/10

Details and patient eligibility

About

This study aims to compare the results of skin testing and ELISPOT assay in patients with a history of non-immediate reactions to cephalosporins

Full description

Patients with a history of non-immediate reactions to cephalosporins will be tested by patch test and/or intradermal test. Peripheral blood mononuclear cells will be collected to analyzed cytokine secretions by ELISPOT assay

Enrollment: 28 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients with a history of non-immediate hypersensitivity reactions to cephalosporins
2. At least 18 years of age

Exclusion criteria

1. Suffering from severe systemic disease/ in bad health
2. Being pregnant
3. Patients with a history of immediate reactions to cephalosporin

Trial design

28 participants in 1 patient group

Cephalosporins allergic patients

Treatment:

Procedure: Skin tests and ELISPOT assay