Sleep Actigraphy in Postural Tachycardia Syndrome (POTS)

Satish R. Raj

Status: Active, not recruiting

Conditions: Sleep Disorders; Orthostatic Intolerance; Postural Tachycardia Syndrome

Treatments: Device: Actigraphy Watch (motion sensors) with light sensors - ActiWatch from Minimitter

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00692471

K23RR020783 (U.S. NIH Grant/Contract)

080233

Details and patient eligibility

About

We propose to use actigraphy (measured by activity watches) as a tool to quantify sleep disturbances in patients with orthostatic intolerance compared with healthy control subjects. In this pilot study, we will test the null hypothesis (Ho) that there are no differences in the sleep quality between patients with orthostatic intolerance and healthy control subjects.

Full description

We propose to use actigraphy (measured by activity watches) as a tool to quantify sleep disturbances in patients with orthostatic intolerance compared with healthy control subjects. In this pilot study, we will test the null hypothesis (Ho) that there are no differences in the sleep quality between patients with orthostatic intolerance and healthy control subjects.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Diagnosed with orthostatic intolerance by the Vanderbilt Autonomic Dysfunction Center
• Control subjects will be free of orthostatic intolerance and other major medical problems, free of medications during the study
• Age between 18-65 years
• Male and female subjects are eligible.
• Able and willing to provide informed consent

Exclusion criteria

• Overt cause for postural tachycardia (such as acute dehydration)
• Self-report of pregnancy
• Inability to give, or withdrawal of, informed consent
• Other factors which in the investigator's opinion would prevent the subject from completing the protocol

Trial design

100 participants in 2 patient groups

1

Description:

Patients meeting the diagnostic criteria for the Postural Tachycardia Syndrome, a form of Orthostatic Intolerance

Treatment:

Device: Actigraphy Watch (motion sensors) with light sensors - ActiWatch from Minimitter

2

Description:

Healthy control subjects who do not meet the criteria for the Postural Tachycardia Syndrome

Treatment:

Device: Actigraphy Watch (motion sensors) with light sensors - ActiWatch from Minimitter