Sleep and Girls' Emotions Study (SAGE)

University of Oregon

Status: Completed

Conditions: Depression

Treatments: Behavioral: Extended sleep opportunity; Behavioral: Typical sleep opportunity

Study type: Interventional

Funder types: Other

Identifiers

NCT04131868

K01MH103511

Details and patient eligibility

About

This study evaluates whether increasing sleep duration can increase neural and behavioral response to rewards and decrease depressive symptoms in 18- to 22-year-old women with insufficient sleep and depressive symptoms.

Enrollment: 34 patients

Sex: Female

Ages: 18 to 22 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Insufficient sleep (total sleep time < 8 hours per night, with sleepiness scores ≥ 6 on the Epworth Sleepiness Scale OR ≥ 16 on the PROMIS Sleep Related Impairment Scale)
• Symptoms of depression (≥ 15 on the Center for Epidemiological Studies for Depression Scale)

Exclusion criteria

• Current insomnia, hypersomnia, sleep disordered breathing, sleep movement disorder, or circadian rhythm disorder
• History of head injury with loss of consciousness within the past two years
• History of head injury with loss of consciousness two or more years ago and meet criteria for post concussion syndrome
• Neurological disorder
• Use of psychiatric medications
• Current psychotic symptoms
• Active suicidal ideation
• Conditions that are contraindicated for MRI (e.g., ferromagnetic material in the body)
• Meet criteria for current substance use disorder with greater than mild severity

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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34 participants in 2 patient groups

Extended sleep opportunity

Experimental group

Treatment:

Behavioral: Extended sleep opportunity

Typical sleep opportunity

Active Comparator group

Treatment:

Behavioral: Typical sleep opportunity