SLeep and IMagery Correlates (SOMMEIL-IMAGERIE)

Civil Hospices of Lyon

Status: Completed

Conditions: Healthy

Treatments: Other: MEG recordings (pre-test); Other: Imagery and Sleep questionnaires; Other: MRI; Other: MEG recordings (Post-test); Other: Practice session

Study type: Interventional

Funder types: Other

Identifiers

NCT03130322

69HCL16_0676

Details and patient eligibility

About

This study is designed to determine the neural networks underlying the sleep-related motor consolidation process following motor imagery practice. While beneficial effects of sleep are expected for sequential movement but not for adaptation motor tasks, the corresponding neuroanatomical correlates have not yet been investigated when participants acquired the motor tasks through mental practice. Data should substantially promote how designing motor imagery interventions targeting (re)learning and/or motor recovery in patients suffering from motor disorders.

Enrollment: 51 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy right-handed persons without neurologic disease
• Persons having signed informed consent for a neuroimagery study

Exclusion criteria

• Persons under curatorship or any administrative/judicial measure
• Participants refusing to be informed of the results of the experiment
• Pregnant women
• Participants with contraindications to the MEG examination: head size, presence of a neurostimulator, steel pivot for the root canal, metallic fragments, ear implants, metal screws in the body or mouth.
• Persons using a pacemaker, insulin pump, or working regularly with iron filings
• Claustrophobic persons

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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51 participants in 4 patient groups

NightPP

Experimental group

Description:

Participants of the NightPP will be subjected to one MRI session and two MEG recording sessions: the first one before a physical practice session of the two motor tasks investigated in the study, and second MEG session right after practice.

Treatment:

Other: Practice session

Other: MEG recordings (Post-test)

Other: MRI

Other: Imagery and Sleep questionnaires

Other: MEG recordings (pre-test)

NightMI

Experimental group

Description:

Participants of the NightMI will be subjected to one MRI session and two MEG recording sessions: the first one before a motor imagery practice session of the two motor tasks investigated in the study, and second MEG session right after practice.

Treatment:

Other: Practice session

Other: MEG recordings (Post-test)

Other: MRI

Other: Imagery and Sleep questionnaires

Other: MEG recordings (pre-test)

NightCtrl

Experimental group

Description:

Participants of the NightCtrl will be subjected to one MRI session and two MEG recording sessions: the first one before a mental rotation practice session, a second MEG session right after practice,and second MEG session right after practice.

Treatment:

Other: Practice session

Other: MEG recordings (Post-test)

Other: MRI

Other: Imagery and Sleep questionnaires

Other: MEG recordings (pre-test)

Day

Experimental group

Description:

Participants of the NightMI will be subjected to one MRI session and two MEG recording sessions: the first one before a motor imagery practice session of the two motor tasks investigated in the study, and second MEG session right after practice.

Treatment:

Other: Practice session

Other: MEG recordings (Post-test)

Other: MRI

Other: Imagery and Sleep questionnaires

Other: MEG recordings (pre-test)