Sleep Characteristics in Post-COVID-19 Patients

Schön Klinik Berchtesgadener Land

Status: Completed

Conditions: Post-COVID-19

Treatments: Diagnostic Test: Sleep diagnostics

Study type: Observational

Funder types: Other

Identifiers

NCT05124548

WHOOP Sleep

Details and patient eligibility

About

After acute infection, patients with coronavirus disease 2019 (COVID-19) often suffer from persisting symptoms for more than 3 months (post COVID-19). Sleep disorders (31%) have already been assessed by questionnaires and interviews in post-COVID-19, but have not yet been proven by polysomnography (PSG), the gold standard for sleep testing. This study aimed to measure sleep characteristics in post-COVID-19 patients.

Full description

Hypothesis: We hypothesize that post-COVID-19 patients have a significantly higher apnea-hypopnea index (AHI) during sleep compared to healthy controls.

15 post-COVID-19 patients and 15 healthy controls will perform a baseline assessment on day 1 including a 1-minute sit-to-stand test (STST), post-COVID functional scale (PCFS), Ordinal Scale for Clinical Improvement (OSCI), history of COVID-19, social anamnesis, Pittsburgh Sleep Questionnaire and subjective limitations of sleep.

On day 4, after an initialization phase for WHOOP strap (a digital fitness and health coach), all patients performed a single night sleep assessment in a sleep lab via Polysomnography and WHOOP.

Enrollment: 31 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Post-COVID-19 Group:

• Patients after SARS-CoV-2 infection with signs of Post-COVID-19
• ≥18 years
• written informed consent

Healthy controls:

• No history of SARS-CoV-2 infection
• ≥18 years
• written informed consent

Exclusion criteria

Post-COVID-19 Group:

• Diagnosis of a breathing-related sleep disorder before SARS-CoV-2 infection
• BMI >25kg/m2

Healthy controls:

• Diagnosis of a breathing-related sleep disorder
• BMI >25kg/m2

Trial design

31 participants in 2 patient groups

Post-COVID condition

Treatment:

Diagnostic Test: Sleep diagnostics

Healthy controls

Treatment:

Diagnostic Test: Sleep diagnostics