Sleep-disordered Breathing and Perioperative Atrial Fibrillation in Cardiac Surgery (CONSIDER-AF)

Michael Arzt

Status: Unknown

Conditions: Coronary Artery Disease; Atrial Fibrillation; Elective Coronary Artery Bypass Grafting (CABG) Surgery; Sleep-disordered Breathing (SDB)

Treatments: Other: Stratification, no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT02877745

3643420

Details and patient eligibility

About

In patients undergoing elective coronary artery bypass grafting (CABG) surgery, coronary artery disease, sleep-disordered breathing (SDB), atrial fibrillation (AF) perioperative atrial fibrillation and complications will be assessed. The primary objective is to determine, whether SDB patients have a higher rate of Major Adverse Cardiac and Cerebrovascular Events (MACCE) within 30 days after surgery compared to those without SDB.

Enrollment: 1,200 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing elective CABG surgery at the Department of Cardiac and Thoracic Surgery, University Hospital Regensburg.
• Written informed consent

Exclusion criteria

• Preoperative use of inotropes or intra aortic balloon pump
• Severe obstructive pulmonary disease
• Patients on oxygen therapy, nocturnal positive airway pressure support or mechanical ventilation

Trial design

1,200 participants in 2 patient groups

no SDB

Description:

apnea-hyponea index \<15/hour

Treatment:

Other: Stratification, no intervention

SDB

Description:

apnea-hyponea index \>=15/hour

Treatment:

Other: Stratification, no intervention