Sleep Disordered Breathing in Children: Inflammation and Oxidative Stress

Tel Aviv Sourasky Medical Center

Status: Unknown

Conditions: Endothelial Dysfunction; Sleep Disordered Breathing (SDB)

Study type: Observational

Funder types: Other

Identifiers

NCT02040701

TASMC-13-RT-06-122-CTIL

Details and patient eligibility

About

The purpose of the study is to measure markers of inflammatory and oxidative stress known to be associated with cardiovascular morbidity in snoring children.

In addition, to measure markers of local inflammation and to evaluate the response to treatment.

Enrollment: 300 estimated patients

Sex: All

Ages: 6 months to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• children ages 6 months-18 years
• suspected sleep-disordered breathing or will attend the pre-operative ENT clinic for adenoidectomy or adenotonsillectomy

Exclusion criteria

• craniofacial abnormalities
• neurological disorders
• genetic disorders
• infectious disease
• chronic inflammatory disease
• any underlying chronic medical condition

Trial design

300 participants in 2 patient groups

SDB group

Control group