Sleep Disorders, Chronotype, and Functional Impairment in the Restrictive ADHD Phenotype

Dr. Behcet Uz Children's Hospital

Status: Completed

Conditions: Morningness Eveningness Preference; Quality of Life; Attention Deficit Disorder With Hyperactivity; Sleep Disorders, Circadian Rhythm

Study type: Observational

Funder types: Other

Identifiers

NCT06970418

832

Details and patient eligibility

About

This study aims to explore chronotype and sleep disturbances in ADHD subtypes and their relation to functional impairment.

Full description

The goal of this observational study is to compare morningness-eveningness and sleep disturbances between children diagnosed with Restrictive ADHD (ADHD-R) and those with Predominantly Inattentive ADHD (ADHD-PI), and to examine how these sleep-related features impact functional impairment.The main question it aims to answer is:Are chronotype differences and sleep disturbances associated with greater functional impairment in children with ADHD-R compared to ADHD-PI and typically developing peers?

Enrollment: 104 patients

Sex: All

Ages: 7 to 12 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age between 7 and 12 years
• Willingness to participate in the study with provided consent
• Diagnosis of ADHD according to the Schedule for Affective Disorders and Schizophrenia for School-Age Children - Present and Lifetime Version - Turkish adaptation (K-SADS); no comorbid psychiatric diagnosis (except Oppositional Defiant Disorder)
• Presence of 6 or more inattention symptoms accompanied by 5 or fewer hyperactivity/impulsivity symptoms on the Disruptive Behavior Disorders Rating Scale based on Diagnostic and Statistical Manual of Mental Disorders-IV
• No psychotropic medication use in the past 3 months

Exclusion criteria

• Families who do not consent to participate in the study
• Children and adolescents with chronic medical conditions and/or currently taking any medications
• Children and adolescents with intellectual disability (mental retardation)
• Children and adolescents with comorbid psychiatric diagnoses
• Presence of a neurological disorder
• History of head trauma

Trial design

104 participants in 3 patient groups

Predominantly Inattentive Presentation (ADHD-PI)

Description:

Patients selected via random sampling from patients either newly admitted to the clinic or already under follow-up for ADHD-PI, with no psychotropic medication use in the last 3 months. All participants were primary or secondary school students. ADHD subtype classification was determined based on Diagnostic and Statistical Manual of Mental Disorders-5 criteria following clinical interviews and scale assessments completed by both parents and teachers. Children with comorbid psychiatric or chronic medical conditions and those using psychostimulants were excluded.

Restrictive Presentation of ADHD

Description:

Patients selected via random sampling from patients either newly admitted to the clinic or already under follow-up for ADHD-R, with no psychotropic medication use in the last 3 months. All participants were primary or secondary school students. ADHD subtype classification was determined based on Diagnostic and Statistical Manual of Mental Disorders-5 criteria following clinical interviews and scale assessments completed by both parents and teachers. Children with comorbid psychiatric or chronic medical conditions and those using psychostimulants were excluded.

control group

Description:

The control group consisted of age- and gender-matched children who presented to the Child and Adolescent Psychiatry clinic, were found to have no psychiatric diagnosis after evaluation, and were considered typically developing. Informed consent and assent forms were obtained from all participants and their legal guardians.