Sleep Disorders in Idiopathic Pulmonary Fibrosis

Wissenschaftliches Institut Bethanien e.V

Status

Completed

Conditions

Idiopathic Pulmonary Fibrosis

Treatments

Diagnostic Test: Sleep study

Study type

Observational

Funder types

Other

Industry

Identifiers

NCT05113654

WI_SleepIPF_169/2015

Details and patient eligibility

About

This diagnostic observational study was conducted to (1) investigate the prevalence of sleep-related breathing disorders and other sleep disorders in idiopathic pulmonary fibrosis in comparison to COPD, (2) identify characteristics of symptomatic and prognostic significance in idiopathic pulmonary fibrosis with/without sleep disorders, and (3) evaluate different tools for their ability to assess the risk of co-existing sleep disorders in idiopathic pulmonary fibrosis.

Enrollment

78 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Age >=18 years
written informed consent
IPF cohort: Documented history of IPF with definite or possible UIP pattern and signs of emphysema below 10% by HRCT (IPF diagnosis according to 2011 ATS/ERS IPF guidelines)
COPD cohort: Documented history of COPD Stage II Group A or B, Stage III or IV, Group C or D (GOLD 2014)

Exclusion criteria

Long-term oxygen therapy
Heart failure NYHA stages III and IV
Left ventricular ejection fraction ≤ 45%
Pregnancy and/or lactation
Acute and/or life-threatening illness (instable angina pectoris, acute pulmonary arterial embolism, myocardial infarction, malignant tumor requiring treatment)
Current drug or alcohol abuse
Any medical, psychological or other condition impairing the patient's ability to provide informed consent
IPF cohort: Acute exacerbation of IPF
IPF cohort: Concomitant lung/airway diseases other than IPF (signs of emphysema >10% by HRCT)
COPD cohort: Acute exacerbation of COPD
COPD cohort: Concomitant lung/airway diseases other than COPD (e.g. Asthma bronchiale)
Healthy cohort: Documented history of structural airway or lung disease