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Sleep Disorders Pre and Post Liver Transplantation

University Health Network, Toronto logo

University Health Network, Toronto

Status

Unknown

Conditions

Liver Cirrhosis

Study type

Observational

Funder types

Other

Identifiers

NCT01002001
REB 09-0459

Details and patient eligibility

About

Sleep disturbance and sexual dysfunction are common complaints of patients with cirrhosis . The term sleep disturbance describes insomnia, poor quality sleep, circadian rhythm disorders and obstructive sleep apnea and is associated with reduced health-related quality of life (HRQoL) score indices. Sleep and sexual disorders have only been formally evaluated in small studies in these patients and to date, no studies have objectively assessed these patients. In addition, no studies have been performed in these patients after liver transplantation. The investigators' hypothesis is that sleep and sexual disturbance is commonly seen in patients with advanced cirrhosis and improves after liver transplantation. However, despite this, HRQoL remain impaired because of residual sleep disturbance.This study will be unique in providing cross-sectional follow-up of patients with cirrhosis at baseline and after liver transplantation (> 6 months).

Enrollment

200 estimated patients

Sex

All

Ages

18 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Liver cirrhosis
  • Comprehend and read English
  • On liver transplantation list or post-liver transplantation

Exclusion criteria

  • Non-English speaking
  • < 18 years and > 85 yrs

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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