Sleep Quality After Nasosinusal Surgery in AERD Patients

National Institute of Respiratory Diseases (INER)

Status: Unknown

Conditions: Aspirin-exacerbated Respiratory Disease; Sleep

Treatments: Procedure: Endoscopic sinus surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT03627481

C34-18

Details and patient eligibility

About

Aspirin exacerbated respiratory disease presents as a triad composed by asthma, eosinophilic rinosinusitis and intolerance to aspirin and NSAIDS. In subjects with chronic rhinosinusitis sleep alterations have been found, with important improvement after surgery, but those alterations and improvements have not been studied in patients diagnosed with AERD who, due to their comorbidities, may present more severe pre surgical symptoms and a more important post-surgical improvement. The investigators aim to study patients with AERD sleep, quality of life and symptoms before surgery, and one, three and six months post-surgery.

Enrollment: 32 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• AERD patients.
• Cumbersome nasal polyposis with poor treatment response

Exclusion criteria

• Previously diagnosed sleep disorder.
• Psychiatric disorder

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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32 participants in 1 patient group

AERD patients

Experimental group

Description:

Patients managed with Endoscopic sinus surgery for treatment of AERD.

Treatment:

Procedure: Endoscopic sinus surgery