Sleep Quality, Daytime Sleepiness and Insomnia in Patients With Endometriosis: a Case-control Study.

IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy

Status: Completed

Conditions: Endometriosis; Sleep

Treatments: Other: The Endometriosis Health Profile.; Other: Insomnia Severity Index.; Other: Pittsburgh Sleep Quality Index.; Other: Epworth sleepiness scale.

Study type: Observational

Funder types: Other

Identifiers

NCT02027142

Sleep and endometriosis.

Details and patient eligibility

About

This study included women referred to two academic centres for the diagnosis and treatment of endometriosis (cases) and women referred to our Institutions because of routine gynaecologic consultations (controls). In this age-matched case-control study, the aimdy was to assess quality of sleep, the average daytime sleepiness and insomnia in patients with endometriosis by using three different self-reported questionnaires.

Enrollment: 290 patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Reproductive age Surgical and histological diagnosis of rectovaginal endometriosis

Exclusion criteria

Suspicion of endometriosis (based on evaluation of symptoms, gynaecological examination and transvaginal ultrasonography) History of infertility Previous diagnosis of endometriosis Gynaecological, intestinal and urological diseases causing abdominal pain (e.g. pelvic congestion syndrome, bladder pain syndrome) Severe underlying comorbidities (cardiovascular, respiratory, renal, hematological, endocrine, hepatic, gastrointestinal, neurological, or psychiatric) Pregnancy at any gestational age Suspicion or diagnosis of oncological pathology Use of gonadotropin releasing hormone analogues (GnRH-a) Restless legs syndrome Shift work Use of antiallergic drugs Narcotics Refusal or inability to sign the informed consent form or complete the study questionnaires

Trial design

290 participants in 2 patient groups

Cases

Description:

Women referred to two academic centres for the diagnosis and treatment of endometriosis.

Treatment:

Other: Insomnia Severity Index.

Other: Pittsburgh Sleep Quality Index.

Other: Epworth sleepiness scale.

Other: The Endometriosis Health Profile.

Controls

Description:

Women referred to our Institutions because of routine gynaecologic consultations.

Treatment:

Other: Insomnia Severity Index.

Other: Pittsburgh Sleep Quality Index.

Other: Epworth sleepiness scale.