Slide Interpretation or Standard Surgical Pathology in Assessing Margin Status in Patients With Pancreatic Cancer Undergoing Surgery

The Ohio State University

Status: Completed

Conditions: Adenocarcinoma; Pancreatic Cancer

Treatments: Other: cytology specimen collection procedure

Study type: Interventional

Funder types: Other

Identifiers

NCT01646697

NCI-2012-00926 (Registry Identifier)

OSU-10110

Details and patient eligibility

About

This study is being done to investigate another way of evaluating margin status after pancreatectomy by using cytopathology (slide interpretation) as compared to the traditional method of surgical pathology

Full description

PRIMARY OBJECTIVES:

I. To compare margin status on final pathology with margin status from cytopathologic evaluation.

OUTLINE:

Patients undergo cytopathologic sample collection during pancreatic resection during which slides are gently pressed against the cut edge of the pancreas, the surgical bed, and along the superior mesenteric artery, and finally against the tumor itself.

Enrollment: 90 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients undergoing pancreatic resection for a presumed, although not necessarily biopsy-proven pancreatic malignancy,
• ages 18 years to 80 years old

Exclusion criteria

• Pregnant women

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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90 participants in 1 patient group

Diagnostic (cytopathologic evaluation)

Experimental group

Description:

Patients undergo cytopathologic sample collection during pancreatic resection during which slides are gently pressed against the cut edge of the pancreas, the surgical bed, and along the superior mesenteric artery, and finally against the tumor itself.

Treatment:

Other: cytology specimen collection procedure