Small Bowel Cleansing Prior to Video Capsule Endoscopy Examination

Queen's University

Status and phase: Completed; Phase 4

Conditions: Endoscopy

Treatments: Drug: Picosalax; Drug: Clear fluids; Drug: Polyethylene glycol

Study type: Interventional

Funder types: Other

Identifiers

NCT00677794

small bowel cleansing and VCE

Details and patient eligibility

About

There remains debate regarding whether small bowel cleansing is required prior to video capsule endoscopy, and if so, which method is best. This study prospectively tests cleansing with no preparation, preparation with picosalax, and preparation with polyethylene glycol.

Enrollment: 198 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients undergoing VCE.

Exclusion criteria

• bowel obstruction or ileus;
• known stricture or fistula;
• previous small bowel surgery;
• severe gastroparesis or motility disorder
• renal impairment (serum creatinine over normal range within three months of study);
• congestive heart failure;
• cirrhosis;
• implanted cardiac pacemaker or defibrillator or other electromedical device;
• pregnancy.

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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198 participants in 3 patient groups

1

Active Comparator group

Description:

Clear fluids only after lunch.

Treatment:

Drug: Clear fluids

2

Active Comparator group

Description:

Two sachets of picosalax the evening prior to Video Capsule Endoscopy (VCE).

Treatment:

Drug: Picosalax

3

Active Comparator group

Description:

Polyethylene glycol, 2 liters the evening prior to Video Capsule Endoscopy (VCE).

Treatment:

Drug: Polyethylene glycol