Small Bowel Motility in Patients With Systemic Sclerosis

Vall d'Hebron University Hospital (HUVH)

Status: Unknown

Conditions: System Sclerosis

Treatments: Diagnostic Test: Endoluminal image analysis by capsule endoscopy

Study type: Interventional

Funder types: Other

Identifiers

NCT05205239

PR(AG)56/2018C

Details and patient eligibility

About

Several studies using intestinal manometry have reported alterations in small bowel motility in patients with systemic sclerosis. Our aim is to apply endoluminal image analysis to stratify the intestinal motor dysfunction in these patients can be assessed by non-invasive techniques. Consecutive patients with systemic sclerosis referred to our institution will be prospectively investigated using automated non-invasive techniques developed in our laboratory. Intraluminal images of the gut were obtained by capsule endoscopy. Endoluminal image analysis will be performed with original, previously validated programs based on computer vision and machine learning techniques.

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Systemic sclerosis diagnosed by ACR criteria

Exclusion criteria

• Lung transplantation
• End stage kidney disease

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Systemic sclerosis

Experimental group

Treatment:

Diagnostic Test: Endoluminal image analysis by capsule endoscopy