Small-Volume Tubes to Reduce Anemia and Transfusion (STRATUS)

Population Health Research Institute (PHRI)

Status: Completed

Conditions: Blood Loss Anemia

Treatments: Device: Small-Volume; Device: Standard-Volume

Study type: Observational

Funder types: Other

Identifiers

NCT03284944

STRATUS Pilot

Details and patient eligibility

About

STRATUS will evaluate the use of small-volume ("soft-draw") blood collection tubes for laboratory testing in reducing anemia and transfusion in intensive care unit patients without significant adverse consequences. This is a simple, cost-neutral intervention that could improve the quality of patient care and reduce the harms of frequent laboratory testing.

Full description

The STRATUS Pilot Study is a prospective observational study (before-after design) to assess the feasibility of implementing a full-scale randomized trial powered for clinical outcomes (RBC transfusion, incidence and severity of anemia). Identification of barriers and facilitators of implementation will enhance the conduct of the full-scale trial and facilitate incorporation of the intervention into routine practice.

Enrollment: 369 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Investigative Site Eligibility:

• Intensive care unit with at least 15 beds with capacity for mechanical ventilation
• Current standard to use standard-draw blood collection tubes
• Availability of hospital administrative data and electronic patient information

Trial design

369 participants in 2 patient groups

Control (Before) Period

Description:

Use of standard-volume blood collection tubes (6 weeks)

Treatment:

Device: Standard-Volume

Intervention (After) Period

Description:

Use of small-volume ("soft-draw") blood collection tubes (6 weeks following 2-week washout period)

Treatment:

Device: Small-Volume