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Smoking Cessation Behavioral Treatment Study

University of Missouri (MU) logo

University of Missouri (MU)

Status

Enrolling

Conditions

Tobacco Use Disorder

Treatments

Behavioral: Mindfulness-Oriented Recovery Enhancement (MORE)
Behavioral: Cognitive Behavioral Therapy (CBT)

Study type

Interventional

Funder types

Other

Identifiers

NCT03948893
2020602

Details and patient eligibility

About

The purpose of this study is to evaluate the effectiveness of two behavioral interventions on smoking behavior - Mindfulness-Oriented Recovery Enhancement (MORE) and Cognitive Behavioral Therapy (CBT). MORE is a behavioral therapy that integrates mindfulness training to modify reward processes. CBT is a therapy designed to help individuals understand how their thoughts and feelings influence their behaviors.

Enrollment

200 estimated patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Age 18 and up
  • English fluency as demonstrated in providing informed consent and the ability to independently follow directions in completing assigned assessments and tasks
  • Functional vision (with corrective lenses as needed) to complete assigned assessments and tasks
  • Current nicotine dependent smoker with a minimum smoking history of 2 years
  • Interest in quitting smoking

Exclusion criteria

  • Use of psychotropic (e.g. antiepileptic) medications in the past month
  • Positive urine drug screen
  • Presence of an untreated medical illness
  • Current or past psychosis
  • History of major neurological illness or head injury resulting in loss of consciousness
  • And contraindication to MRI, including claustrophobia
  • Among females, positive urine pregnancy test
  • Inability or unwillingness of subject to give informed consent

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

200 participants in 2 patient groups

MORE
Experimental group
Treatment:
Behavioral: Mindfulness-Oriented Recovery Enhancement (MORE)
CBT
Active Comparator group
Treatment:
Behavioral: Cognitive Behavioral Therapy (CBT)

Trial contacts and locations

2

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Central trial contact

Madhura Athreya, MS; Brett Froeliger, PhD

Data sourced from clinicaltrials.gov

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