Smoking Cessation in the Surgical Pathway Before Major Lung Surgery (MURRAY)

University of Birmingham

Status: Unknown

Conditions: Smoking Cessation; Thoracic Surgery

Treatments: Device: Integrated Web-based application; Behavioral: Integrated Behavioural therapy; Drug: Integrated Pharmacotherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT04190966

Worktribe 843842

Details and patient eligibility

About

This is a feasibility study of a personalised, integrated smoking cessation in the surgical pathway in patients undergoing major elective thoracic surgery when compared to usual care of standard community/hospital based NHS smoking cessation. Half the patients will receive the intervention and half the patients will receive usual care.

Full description

Smoking prior to major thoracic surgery is a major risk factor for development of postoperative complications which effect both short and long-term outcome. Despite this 1 in 5 patients continue to smoke before their operation.

Project MURRAY is a trial comparing the effectiveness of personalised integrated smoking cessation delivered by trained health-care practitioners in the thoracic surgical pathway, and is a three part package of behaviour interventions and pharmacotherapy as per National Institute of Clinical Excellence (NICE)/ National Centre for Smoking Cessation Training (NCSCT) guidance which is supported by an adjunct web-based application. This is a pilot study to evaluate feasibility of a substantive trial and study processes in 5 adult thoracic centres including the trial coordinating site at the University Hospitals Birmingham NHS Foundation Trust. This is a multicentre feasibility study, with aim for equal weighting between the two arms of the integrated smoking cessation and an observation only group of usual care.

Enrollment: 120 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Current tobacco smoker (smoked within the last 28 days)
• Major Thoracic Surgery (including both open and minimally invasive approach)
• Able to provide written informed consent
• At least 1 weeks' time to surgery
• Age over 18 years

Exclusion criteria

• Emergency thoracic surgery
• Inability to perform exhaled carbon monoxide (CO) measurements

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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120 participants in 2 patient groups

Integrated smoking cessation

Active Comparator group

Description:

Integrated smoking cessation delivered by trained health-care practitioners in the thoracic surgical pathway: a three part package of behaviour interventions and pharmacotherapy as per NICE/NCSCT guidance which is supported by an adjunct web-based application.

Treatment:

Device: Integrated Web-based application

Drug: Integrated Pharmacotherapy

Behavioral: Integrated Behavioural therapy

Usual care smoking cessation

No Intervention group

Description:

Usual care of standard community/hospital based NHS smoking cessation.