Smoking Cessation Study

McGill University

Status: Enrolling

Conditions: Smoking Cessation; Arthropathy

Treatments: Behavioral: Lifestyle Counseling

Study type: Observational

Funder types: Other

Identifiers

NCT05602753

2020-6424

Details and patient eligibility

About

The primary outcome of this study is to determine the true incidence of smokers among patients undergoing joint replacement and secondly, what percent are able to quit smoking before surgery under a structured cessation program with carbon monoxide breath testing. The investigators hypothesize that self-reported smoking status is underreported and that routine carbon monoxide breath testing will improve abstinence rates at the time of surgery.

Full description

This study looks at patients who have been referred to our clinic for a potential hip and knee joint replacement surgery. Once it has been determined that the patient requires surgical replacement of either their hip or knee and is placed on our surgical waitlist, the patient will be asked if he or she would like to participate in the study. The investigators would ask all patients, both self-declared smokers and non-smokers, to participate. This study would include completing a smoking history questionnaire and a noninvasive carbon monoxide breath test. While smoking status is already assessed in the McGill University Health Centre preoperative questionnaire, the investigators intend on expanding these questions in study participants to better quantify their nicotine exposure.

Enrollment: 300 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults ages 18-85 who require a primary total hip or knee replacement
• Any gender
• Smokers and non-smokers
• Osteoarthritis, rheumatoid arthritis, avascular necrosis

Exclusion criteria

• Patients who require revision surgery
• Previous fracture to affected area
• Emergency surgery
• Patients who do not understand, read or communicate in either French or English

Trial design

300 participants in 3 patient groups

Smokers

Description:

All patients who participate in the study will complete the smoking history questionnaire and the carbon monoxide breath test. All patients with positive carbon monoxide breath test indicative of active nicotine exposure will be provided a structured smoking cessation program that includes information, counseling from their surgeon, or a trained health care professional and referral to a smoking cessation program.

Treatment:

Behavioral: Lifestyle Counseling

Non-Smokers

Description:

Subjects who self-declared as non-smokers

Declared non-smokers with elevated Co2

Description:

subjects who self-declared as non-smokers but who tested positive for elevated Co2,