SMS Reminders to Strengthen Demand for HPV Vaccination in Georgia

The Behavioural Insights Team

Status: Not yet enrolling

Conditions: HPV, Human Papillomavirus Viruses, Human Papilloma Virus Vaccine

Treatments: Behavioral: SMS reminder for the HPV vaccination

Study type: Interventional

Funder types: Other

Identifiers

NCT05536674

UNICEF Georgia 2020021

Details and patient eligibility

About

It is possible that achieving adequate HPV vaccination coverage will allow cervical cancer to be virtually eliminated. This is a priority for Georgia, where the burden of mortality and morbidity from cervical cancer is high and the yearly prevalence of cervical cancer is 14.5 per 100,000 population.

The objective of the intervention evaluated is to increase the uptake of the 1st dose of the HPV vaccination in Georgia. The intervention aims to achieve this by providing a SMS reminder informed by behavioural insights (BI) to remind caregivers of girls between 10-12 years that their daughter is due the first dose of her HPV vaccination, share information about the vaccine, and encourage them to book an appointment to receive the vaccination. Four different SMS messages will be compared to no SMS message.

The evaluation will be a 5-arm randomised controlled trial (RCT) which aims to answer the research question: Does each of the designed BI-informed SMS reminders increase the uptake of the first dose of the HPV vaccination among eligible girls in Georgia, compared to no reminder? Our hypothesis is that SMS reminders will increase the uptake of HPV vaccination.

Enrollment: 55,176 estimated patients

Sex: Female

Ages: 10 to 12 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Girls
• Aged 10-12 years
• Not yet received any doses of the HPV vaccine
• With a caregiver's mobile phone number in the e-health system.

Exclusion criteria

• Boys
• Girls aged less than 10 or more than 12 years
• Girls with no caregiver phone number in the e-health system
• Girls who have received 1 or 2 doses of the HPV vaccine

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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55,176 participants in 5 patient groups

No SMS reminder

No Intervention group

Description:

This group will receive no reminder

Short SMS with no additional information

Experimental group

Description:

Caregivers of girls eligible to receive the HPV vaccination in this group will receive an SMS reminder that states: "As per national immunization calendar your daughter is due her free human papilloma virus vaccine, which will protect her against cervical cancer. Contact your family doctor today to arrange an appointment."

Treatment:

Behavioral: SMS reminder for the HPV vaccination

Short SMS + NCDC link

Experimental group

Description:

Caregivers of girls eligible to receive the HPV vaccination in this group will receive an SMS reminder that states: "As per national immunization calendar your daughter is due her free human papilloma virus vaccine, which will protect her against cervical cancer. Contact your family doctor today to arrange an appointment. More information on the official NCDC website"

Treatment:

Behavioral: SMS reminder for the HPV vaccination

SMS with "reserved for her" framing + NCDC link

Experimental group

Description:

Caregivers of girls eligible to receive the HPV vaccination in this group will receive an SMS reminder that states: "As per national immunization calendar your daughter is due her free human papilloma virus vaccine, which will protect her against cervical cancer. Her vaccine is reserved at the policlinic. Contact your family doctor today to arrange an appointment. More information on the official NCDC website"

Treatment:

Behavioral: SMS reminder for the HPV vaccination

SMS with safety information + NCDC link

Experimental group

Description:

Caregivers of girls eligible to receive the HPV vaccination in this group will receive an SMS reminder that states: "As per national immunization calendar your daughter is due her free human papilloma virus vaccine, which will protect her against cervical cancer. The vaccine has been given safely to more than 118 million girls worldwide. Contact your family doctor today to arrange an appointment. More information on the official NCDC website"

Treatment:

Behavioral: SMS reminder for the HPV vaccination