SNAP VS BIS(OAA/S) Scale During a Sedation Regimen With and Without Ketamine

Northwestern University

Status: Terminated

Conditions: Pain

Treatments: Drug: Ketamine group

Study type: Interventional

Funder types: Other

Identifiers

NCT01250418

STU00031783

Details and patient eligibility

About

The study question: Does the SNAP-Index (SI) correlates better with the OASS than the BIS Monitor during sedation with ketamine?

The study hypothesis: Since the SNAP II monitor seems to be more responsive during emergence of anesthesia, it will have a better correlation with the OASS than the BIS monitor with the use of ketamine.

Enrollment: 25 patients

Sex: Female

Ages: 18 to 64 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age : 18-64 years
• ASA : I-III
• Procedure : Breast or gynecological surgery
• Anesthesia :Monitored anesthesia care

Exclusion criteria

• Pregnancy

• Breast Feeding

• Body Mass Index >35kg/m2

• Drug or Alcohol abuse

• Use anticonvulsants

• History of CVA

• Drop-out criteria:

  • Patient or surgeon request
  • Conversion to general anesthesia
  • Inability to obtain data from both monitors

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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25 participants in 2 patient groups

Ketamine Group

Active Comparator group

Description:

ketamine bolus of 0.25mg/kg followed by an infusion set at 1.5 mcg /kg/min.

Treatment:

Drug: Ketamine group

No ketamine

No Intervention group

Description:

No ketamine added to anesthesia regimen