Social Anxiety Virtual Reality Study (SAVR)

Stanford University

Status: Terminated

Conditions: Social Anxiety Disorder

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04288180

IRB-48367

Details and patient eligibility

About

This project aims to validate a virtual reality paradigm that assesses maladaptive avoidance behavior in social anxiety disorder. It also aims to generate a significant scientific advance by testing the hypothesis that maladaptive avoidance maintains anxiety through disruptions in safety learning.

Full description

Although occasional mild social anxiety is a common human experience, social anxiety disorder has a devastating impact on patients' lives, leaving them vulnerable to medical, psychiatric, and socioeconomic complications. A key feature of social anxiety disorder is avoidance of social and/or performance situations in which judgment and evaluation from others might occur. Reducing avoidance is therefore an important treatment goal.

Despite the importance of avoidance, however, it is very difficult to assess a patient's tendency to avoid. Many prior assessments of avoidance measure adaptive (i.e., helpful) avoidance, in which an individual learns to avoid a truly noxious stimulus. However, anxiety disorders are characterized by maladaptive avoidance, in which a relatively safe stimulus is avoided resulting in interference with the individual's goals. In this study, the first aim is to validate a virtual reality paradigm to measure maladaptive avoidance behavior in adults with social anxiety disorder. The second aim is to test whether maladaptive avoidance behavior relates to safety learning (measured by a fear extinction task).

Enrollment: 4 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age 18+
• primary diagnosis of social anxiety disorder
• fluent spoken and written English
• able to provide informed consent

Exclusion criteria

• history of manic episode, hypomanic episode, or psychosis
• moderate or severe substance use disorder in the past 12 months
• current major depressive episode greater than moderate severity (PHQ-9 score >14)
• high risk for suicide (>8 on the MINI Suicidality section and/or clinician judgment that immediate medical attention is necessary)
• general medical condition or impediment to vision, hearing, or motor function likely to interfere with assessments
• benzodiazepine use in the past 2 weeks
• cannabis use for anxiety management in the past 2 weeks

Trial design

4 participants in 1 patient group

Social Anxiety Disorder

Description:

A group of adults with social anxiety disorder will be recruited for a psychological/behavioral research study.

Treatment:

Other: No intervention