Social Cognition in Longstanding Psychosis

University of Arizona

Status: Terminated

Conditions: Psychosis Not Otherwise Specified (NOS); Schizophrenia; Bipolar Disorder With Psychotic Features; Schizoaffective Disorder; Major Depression With Psychotic Features

Study type: Observational

Funder types: Other

Identifiers

NCT01624831

U. Az IRB 11-0567-02

Details and patient eligibility

About

In the current study, the investigators propose to measure the five domains of social cognition identified by the National Institute of Mental Health (NIMH) as relevant to individuals with psychosis (i.e., theory of mind, attribution style, emotion recognition, social perception, and social knowledge). The investigators will also explore the association between different domains of social cognition and outcomes relevant to psychotic disorder (e.g., symptomatology, social functioning, and vocational functioning).

Full description

There is growing evidence that individuals with longstanding psychotic disorders suffer from deficits in social cognition (i.e., the cognitive skills needed to successfully navigate social interactions). However, to date, there have been few attempts to measure multiple components of social cognition within the same population of individuals with psychosis. Thus, the interrelationships between various aspects of social cognition remain unclear. In the current study, the investigators propose to measure the five domains of social cognition identified by NIMH as relevant to individuals with psychosis (i.e., theory of mind, attribution style, emotion recognition, social perception, and social knowledge). The investigators will also explore the association between different domains of social cognition and outcomes relevant to psychotic disorder (e.g., symptomatology, social functioning, and vocational functioning).

Enrollment: 9 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of a schizophrenia spectrum disorder or an affective disorder with psychotic features per the Diagnostic and Statistical Manual of Mental Disorders-IV-Text Revised (DSM-IV-TR) criteria using the Structured Clinical Interview for the DSM-IV.
• Duration of psychotic symptoms greater than or equal to 5 years determined using the Symptom Onset in Schizophrenia Inventory
• Age 18-75
• No evidence of mental retardation.
• Able to provide informed consent as evidenced by passing the informed consent quiz with a score of 80% or greater.
• Fluent in English as assessed per self-report from participant

Exclusion criteria

• Unwilling or unable to complete study assessments (e.g., unable to read self-report questionnaires)
• Subject is currently pregnant per subject's report

Trial design

9 participants in 1 patient group

Individuals with Longstanding Psychosis

Description:

Individuals with symptoms of psychosis that have been present for 5 or more years