Social Feedback and Dysfunctional Risk Taking in NSSI Adolescents

University of Electronic Science and Technology of China

Status: Enrolling

Conditions: Nonsuicidal Self Injury; Risk-Taking

Study type: Observational

Funder types: Other

Identifiers

NCT05981677

BAM_lab_NSSI_03

Details and patient eligibility

About

Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Problematic interpersonal relationships and decision-making have been demonstrated to play crucial roles in this maladaptive behavior, especially for adolescents. Accumulating evidence suggests that decision processes and risk-taking are strongly influenced by the affective state of the individual. However, whether these interactions are disrupted in NSSI adolescents has not been systematically examined. In the current study, the investigators modified one of the most widely used paradigms for measuring an individual's risk decision-making, the Balloon Analogue Risk Task (BART). The investigators combine social reward (green balloon), punishment (red balloon), and control feedback (yellow balloon), to investigate whether the NSSI adolescents have dysfunctional risk-taking behavior while facing different social outcomes. The investigators recruit one group of NSSI adolescents (n = 40) and one health control (HC) group (n = 40), to compare their risk-related decisions during the emotional BART. The investigators hypothesize that compared to HC, NSSI adolescents will show altered effects of social reward and punishment on risk-related decision-making, in particular higher risk avoidance in the context of social punishment.

Enrollment: 80 estimated patients

Sex: All

Ages: 15 to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 15-18 years
• right-handed
• normal or corrected normal visual acuity
• meet the proposed DSM-5 frequency criteria (e.g., ≥5 days of NSSI behaviors in the past year)

Exclusion criteria

• diagnosis of borderline personality disorder, major depressive disorder, other
• psychiatric disorders, etc.
• high suicidal risk
• recent use of medications that can affect neural activity
• have received or are receiving Dialectical Behavior Therapy (DBT) other treatment for emotional problems within the past 6 months
• have a contraindication to MRI scanning (e.g., metal implants, claustrophobia or other conditions that make them inappropriate for MRI scanning)

Trial design

80 participants in 2 patient groups

NSSI

HC