Social Media-based Active Self-report on Incidence and Outcomes of Adverse Events in NK/TCL Patients

Rong Tao

Status: Completed

Conditions: Extranodal NK-T-Cell Lymphoma, Nasal Type

Treatments: Combination Product: L-Asparaginase or or Pegaspargase containing chemotherapy

Study type: Observational

Funder types: Other

Identifiers

NCT03079544

XHLSG-NK-1603

Details and patient eligibility

About

The purpose of this study is to collect data from patients by social media and self-report on the adverse events and outcomes happened with patients with extranodal natural killer/T-cell lymphoma, nasal type, who are treated outside of clinical trials in China.

Full description

Extranodal natural killer/T-cell lymphoma, nasal type, is a rare subtype of non-Hodgkin lymphoma with relatively high incidence in China. L-asparaginase based chemotherapy are widely used with Chinese patients and has been reported to improve overall response and prolonged the long-term survival in some clinical trials with very limited patients. However, most patients were treated out of clinical trials in China. Therefore the real incidence of adverse events and treatment outcomes are largely unknown. This study is designed to evaluate the incidence of adverse events and treatment outcomes by social media-based (www.house086.com, www.wechat.com) self-report from patients who are treated out of clinical trials.

Enrollment: 665 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pathological diagnosis of extranodal natural killer/T-cell lymphoma, nasal type based on WHO 2008 classification of tumors of haematopoietic and lymphoid tissue.
• Treated with at least one cycle of L-asparaginas or Pegaspargase based chemotherapy.
• Signed Informed consent.

Exclusion criteria

• patients who are enrolled in any other clinical trials.
• Relapsed patients who were initially treated with non-L-asparaginas or non-pegaspargase based regimens.