Socioeconomic Status, Secondary Prevention Activities and Recurrence After a Myocardial Infarction

Karolinska Institute

Status: Completed

Conditions: Stroke; Myocardial Infarction; Socioeconomic Status; Secondary Prevention; Cardiovascular Disease

Study type: Observational

Funder types: Other

Identifiers

NCT04199663

3

Details and patient eligibility

About

This is a nationwide cohort study on real-world patients (n≈30,000) surviving a first myocardial infarction (MI) 2006-2013 and alive to attend a routine 1-year follow-up. Associations between Socioeconomic Status (SES) and secondary preventive actions (SPAs) throughout the first year is studied and assessed as possible mechanisms underlying the increased risk of a first recurrent hard cardiocvascular (CV) outcome, recurrent atherosclerotic cardiovascular disease (rASCVD), in patients with low Socioeconomic Status during long-term follow-up (2006-2018).

Enrollment: 30,191 patients

Sex: All

Ages: 18 to 76 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Swedish resident
• Alive and registered in The Swedish Websystem for Enhancement and Development of Evidence based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART)'s secondary prevention subregistry between 1 January 2006 and 31 December 2013 at the 1-year-revisit

Exclusion criteria

• Age >76 years at baseline
• Missing data for disposable household income
• History of MI, stroke, coronary artery bypass graft (CABG), or percutaneous coronary intervention (PCI) prior to the index MI
• Not present in initial care registry (RiksHIA)
• Date of index MI before 2004 or missing
• revisit outside 13±2 month window post-MI

Trial design

30,191 participants in 1 patient group

categories of Socioeconomic Status (SES)

Description:

by proxy gender- and calendar year-specific quintiles of disposable income per household consumption unit. In logistic regression models of associations with secondary prevention activities and established treatment goals: highest vs. lowest income quintile. In multivariable Cox regression analyses with stepwise built models: quintiles of disposable income and models including covariates level of education and marital status.