Socket Preservation Using Autogenous Bone Graft Versus MPM

Cairo University (CU)

Status and phase: Unknown; Phase 2; Phase 1

Conditions: Bone Graft; Complications

Treatments: Other: Autogenous Bone Graft; Other: MPM(Mineralized plasmatic matrix).

Study type: Interventional

Funder types: Other

Identifiers

NCT03008538

CairoSPR-Aut

Details and patient eligibility

About

Studying the comparative effectiveness of socket preservation using autogenous bone graft versus MPM for implant insertion.

Full description

To assess bone quality, stability of implants placed in fresh extraction sockets of mandibular anterior and premorals augmented by MPM (Mineralized Plasmatic Matrix) versus autogenous bone graft (gold standard), at different follow-up periods (0, 3, 6, 9 months).

Enrollment: 20 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Medically free patients.
2. Patients with mandibular anterior and premolar hopeless teeth indicated for extraction.
3. Evaluated bone height on X.Ray to be (0-4 mm buccal bone dehiscence).
4. Age between 18 and 40 years.
5. Both sexes.
6. Patients physically able to tolerate surgical and restorative procedures. Good oral hygiene.
7. Highly motivated patients.

Exclusion criteria

1. Smokers.
2. Pregnant or lactating females.
3. Presence of any pathosis in the pre-implant site.
4. Presence of Para functional habits.
5. History of oral radiotherapy.
6. History of prolonged steroids use
7. Psychological disorders.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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20 participants in 2 patient groups

Mineralized Plasmatic Matrix

Experimental group

Description:

MPM(Mineralized plasmatic matrix) insertion in extraction sockets for socket preservation for later implant placement and histomorphometric analysis.

Treatment:

Other: MPM(Mineralized plasmatic matrix).

Autogenous Bone Graft (Gold Standards).

Active Comparator group

Description:

Socket preservation using Autogenous bone graft for later implant placement and histomorphometric analysis.

Treatment:

Other: Autogenous Bone Graft