Sodium Alginate in Chocolate Milk, Satiety and Glycemic Control

University of Toronto

Status: Completed

Conditions: Health; Glucose Metabolism; Appetite Regulation

Treatments: Other: Dietary intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT01877460

26942

Details and patient eligibility

About

This study compares the effects of isovolumetric (325 ml) preloads of chocolate milk supplemented with sodium alginates at incremental doses on inter-meal glucose levels, appetite scores and food intake in healthy adult men. The findings of this study will illustrate whether the addition of sodium alginate to chocolate milk will improve the glycemic properties of chocolate milk and will potentiate its satiating characteristics. This study will also elucidate whether sodium alginates, incorporated into chocolate milk, will influence glycemia, appetite sensations and food intake in a dose-dependent manner. It is hypothesized that there will be a synergy between milk and sodium alginate beyond either alone. When combined with milk components, sodium alginate is expected to improve glycemia and induce satiety more than does either milk alone or alginate alone.

Enrollment: 24 patients

Sex: Male

Ages: 20 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy,
• non-smoking male subjects,
• aged 20-30 years with a body mass index between 20 and 24.9 kg/m2, were recruited.

Exclusion criteria

• Breakfast skippers,
• smokers,
• dieters,
• individuals with lactose-intolerance or
• who are allergic to milk,
• individuals with gastrointestinal problems and
• individuals with diabetes or other metabolic diseases were excluded from the study.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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24 participants in 4 patient groups

Sodium alginate-free chocolate milk

Experimental group

Description:

Sodium alginate-free chocolate milk (1% fat) (Beatrice Ltd., Toronto, Ontario)

Treatment:

Other: Dietary intervention

1.25% sodium alginate chocolate milk

Experimental group

Description:

Chocolate milk (Beatrice Ltd., Toronto, Ontario) with 1.25% sodium alginate

Treatment:

Other: Dietary intervention

2.5% sodium alginate chocolate milk

Experimental group

Description:

Chocolate milk (Beatrice Ltd., Toronto, Ontario) with 2.5% sodium alginate

Treatment:

Other: Dietary intervention

2.5% sodium alginate milk-free water-based solution

Experimental group

Description:

Water solution with 2.5% sodium alginate

Treatment:

Other: Dietary intervention