Sodium Intake in Multiple Sclerosis (SALT)

Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia

Status: Completed

Conditions: Multiple Sclerosis

Study type: Observational

Funder types: Other

Identifiers

NCT01846234

Salt

Salt-1 (Other Grant/Funding Number)

Details and patient eligibility

About

Recently, it has been shown that salt (ClNa, sodium chloride) can modulate the differentiation of human and mouse TH17 cells. Indeed, mice feed with high sodium diet were described to develop more aggressive course of EAE (Experimental Autoimmune Encephalitis).

However, the role of sodium intake in MS has not been investigated. In this study we investigate the effect of sodium intake in Multiple Sclerosis (MS) clinical and radiological activity.

Enrollment: 132 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subject is between 18 and 50 years old
• Subject has diagnosis of relapsing-remitting MS according to McDonald criteria (2010)

Exclusion criteria

• Patient who had hyponatremia in the last 90 days

Trial design

132 participants in 1 patient group

MS patients

Description:

MS patients