Sodium Management in Acute Neurological Injury (SANI)

The Washington University

Status: Completed

Conditions: This Study is to Understand the Current Practice of Sodium Management in Acute Neurological Injury

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT01558843

201203034

Details and patient eligibility

About

This multicenter, observational, study will enroll severe neurologically injured patients both prospectively and retrospectively. The aims are to identify the percent of neurocritical care patients with sodium levels ≤ 135 mEq/L, describe treatment strategies employed, determine the correlation of clinical factors (i.e. GCS, ICP) with serum sodium concentrations in patients prior to sodium altering therapy, and evaluate outcomes through evaluation of length of stay, discharge disposition, and modified Rankin score (mRS).

Enrollment: 400 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• age ≥ 18 years of age
• admitted to an intensive care unit for more than 48 hours
• ICD-9 codes for aneurysmal SAH, TBI, IPH, or intracranial tumor.

Exclusion Criteria:

Trial design

400 participants in 4 patient groups

traumatic brain injury

aneurysmal subarachnoid hemorrhage

intracerebral hematoma

brain tumor