Sonographic Signs of Gouty Arthritis in a Cohort of Egyptian Patients: a Cross Sectional Multicenter Study

Sohag University

Status: Completed

Conditions: Sonographic Signs of Gouty Arthritis in Diagnosed and Suspected Patients

Treatments: Diagnostic Test: Evaluation of sonographic signs of gouty arthritis

Study type: Observational

Funder types: Other

Identifiers

NCT04734093

21130

Details and patient eligibility

About

The study is a cross sectional observational multicenter study. It is established in collaboration with the Egyptian college of rheumatology study group (ECRsg). It is conditioned that all the study participants had either mono- or oligo-arthritis with effusion of the knee or the first metatarsophalangeal (MTP) joint in patients with a known history of gout or at high risk. Patients with any known chronic arthritis, comprising rheumatoid arthritis, Sjogren's syndrome, systemic lupus erythematosus, scleroderma, neuropathic arthritis, seronegative spondyloarthropathy, will be excluded from the study. None of the participants had a history of intra-articular injection or aspiration in the scanned joints for 3 months prior to the inclusion in the study. The sonographers will be blinded for clinical data and the EULAR scanning protocol for the knee and 1st MTP will be considered [2]. Further, scanning of the double contour sign over the femur condyles anteriorly and posteriorly in sagittal planes will be assessed. All the sonographers in the study had an experience between 5 and 10 years in the field of musculoskeletal ultrasound.

Enrollment: 300 patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• mono- or oligo-arthritis with effusion of the knee or the first metatarsophalangeal
• patients with a known history of gout or at high risk

Exclusion criteria

• Patients with any known chronic arthritis, comprising rheumatoid arthritis, Sjoegren's syndrome, systemic lupus erythematosus, scleroderma, neuropathic arthritis, seronegative spondyloarthropathy
• History of intra-articular injection in the last 3 months.

Trial design

300 participants in 8 patient groups

Sohag university recruited patients

Treatment:

Diagnostic Test: Evaluation of sonographic signs of gouty arthritis

Minia university recruited patients

Treatment:

Diagnostic Test: Evaluation of sonographic signs of gouty arthritis

Assuit university recruited patients

Treatment:

Diagnostic Test: Evaluation of sonographic signs of gouty arthritis

Kasr Elini recruited patients

Treatment:

Diagnostic Test: Evaluation of sonographic signs of gouty arthritis

Tanta university recruited patients

Treatment:

Diagnostic Test: Evaluation of sonographic signs of gouty arthritis

Monofia university recruited patients

Treatment:

Diagnostic Test: Evaluation of sonographic signs of gouty arthritis

Aswan university recruited patients

Treatment:

Diagnostic Test: Evaluation of sonographic signs of gouty arthritis

Ain shams university recruited patients

Treatment:

Diagnostic Test: Evaluation of sonographic signs of gouty arthritis