Sonography-guided Pericapsular Never Group Block for Hip Arthroplasty (QUASH)

Guangzhou First People's Hospital

Status: Unknown

Conditions: Arthroplasty; Nerve Block; Analgesia

Treatments: Procedure: pericapsular nerve group block

Study type: Interventional

Funder types: Other

Identifiers

NCT04480320

K-2020-085-01

Details and patient eligibility

About

In this study, the investigator will examine the efficacy of Pericapsular nerve group (PENG) block in hip arthroplasty as a post-operative pain management technique, study the analgesia, opioid-sparing effects and motor-blocking effects of the PENG block

Full description

PENG Block group (PG) will receive 0.5%Ropivacaine in 20 ml of saline. Sham Block group (SG) will receive 20 ml of saline Patient will be sedated with IV midazolam before nerve block. After peripheral nerve block ,general anesthesia will be conducted using sufentanyl, propofol and rocuronium for induction and propofol and sevoflurane for maintenance. Tests will be operated after procedure，and recorded up to 48 hours after surgery.

Enrollment: 71 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients scheduled for hip arthroplasty

Exclusion criteria

• allergy to local anesthetics
• infection at the injection site
• patients receiving opioids for chronic analgesic therapy
• other lower limb neuropathies
• inability to comprehend visual analog scale (VAS)
• preexist cognitive dysfunction

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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71 participants in 2 patient groups, including a placebo group

Pericapsular nerve group block

Experimental group

Treatment:

Procedure: pericapsular nerve group block

Saline placebo group

Placebo Comparator group

Treatment:

Procedure: pericapsular nerve group block