Specific Methylation Profiles in HNSCC

Aalborg University Hospital

Status: Enrolling

Conditions: Head and Neck Squamous Cell Carcinoma

Treatments: Diagnostic Test: Blood sample

Study type: Observational

Funder types: Other

Identifiers

NCT04567056

N-20190047-2

Details and patient eligibility

About

In the study, N-20190047, the investigators aim to define specific methylation patterns in a group of patients with head and neck squamous cell carcinomas.

With this study the investigators aim to validate these findings in a larger cohort.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Cancer group:

Inclusion Criteria:

• Written informed consent
• Verified head and neck squamous cell carcinoma

Exclusion Criteria:

• Other active cancer
• Uncontrolled comorbidity
• Unable to give informed consent

Control group:

Inclusion Criteria:

• Written informed consent
• Normal ENT-examination

Exclusion Criteria:

• Other active cancer
• Uncontrolled comorbidity
• Unable to give informed consent

Trial design

300 participants in 2 patient groups

Cancer group

Description:

Patients with verified head and neck squamous cell carcinomas

Treatment:

Diagnostic Test: Blood sample

Control group

Description:

Matched control group without active or earlier cancer and a normal ENT examination.

Treatment:

Diagnostic Test: Blood sample