Speech and Language Therapy After Stroke

The University of Chicago

Status: Terminated

Conditions: Ischemic Stroke

Treatments: Behavioral: Imitate Therapy

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00713050

13785A

5R01DC007488-05 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

Our overall goal is to advance the state of functional brain imaging in aphasia, and then to apply the method to an intensive, imitation-based treatment for non-fluent aphasia.

Full description

Detailed information will follow in the next progress report.

Enrollment: 34 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Single ischemic infarction in the MCA territory involving the cerebral cortex (confirmed by CT or MRI)
2. Aphasia
3. Visual attention and language comprehension sufficient to perform imitation fMRI tasks
4. Right handed (prior to stroke)

Exclusion criteria

Exclusions to the study are people with cardiac pacemakers, claustrophobia, neurosurgical clips, or cognitive impairments too severe to permit cooperation with cognitive tasks in an MRI scanner.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind

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34 participants in 2 patient groups

Experimental

Experimental group

Description:

Computer-based Aphasia therapy

Treatment:

Behavioral: Imitate Therapy

Control

Active Comparator group

Description:

Control Arm - Healthy subjects.

Treatment:

Behavioral: Imitate Therapy