Speech, Linguistic and Acoustic Markers in Parkinson's Disease (SLAM-PD)

University of Massachusetts, Worcester

Status

Completed

Conditions

Parkinson Disease

Speech

Cognitive Impairment, Mild

Treatments

Diagnostic Test: Cognitive Battery

Behavioral: Voice, Speech and Language Analysis

Behavioral: Questionnaires and Clinical Assessments

Genetic: DNA Analysis

Study type

Observational

Funder types

Other

Other U.S. Federal agency

NIH

Identifiers

NCT04273672

5K23DC016656 (U.S. NIH Grant/Contract)

H00011523

Details and patient eligibility

About

The Investigators aim to identify speech and language markers that provide information on cognitive function and predict cognitive decline in Parkinson's disease. The Investigators will administer speech tasks and cognitive assessments to participants with Parkinson's disease and healthy controls. The Investigators will also explore the associations between genetic factors and speech and cognitive status in Parkinson's disease.

Enrollment

58 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Parkinson's Disease (or healthy control)
Disease duration ≥ 2 years
Mild cognitive impairment or normal cognition

Exclusion criteria

Diagnosis of dementia (MoCA <21)
Adults unable to consent
Age < 18
Pregnant women
Prisoners
Non-English speakers
Any neurological disorder other than PD
Deep brain stimulator placement
Severe, unstable psychiatric disorder
Unintelligible speech due to effects of PD
Visual acuity or color vision impairment that would interfere with cognitive testing
Other voice, speech or swallowing disorders or history of surgery involving palate/nasopharynx/larynx/vocal cords