ClinicalTrials.Veeva

Menu

Speeded Anomia Treatment in Chronic Post-stroke Aphasia

U

University of Cambridge

Status

Enrolling

Conditions

Aphasia

Treatments

Behavioral: Speeded anomia therapy

Study type

Interventional

Funder types

Other

Identifiers

NCT05512884
01/8/094

Details and patient eligibility

About

The main aim of the study is to investigate the effect of a novel, speeded anomia therapy (Conroy et al., 2018) in a large population of patients with chronic post-stroke aphasia. The treatment will be delivered via a web application (QuickWord).

Full description

The main aim is to test the clinical efficacy of a novel, web based, rehabilitation approach to aphasic word-finding difficulties (QuickWord). In an initial development and case-series evaluation, Conroy et al (2018, Brain) found that training for both speed as well as accuracy of naming generated much better outcomes to picture naming accuracy and also augmented the carry-over to connected speech production.

This is a randomised, crossover, clinical trial of QuickWord in a group of aphasic patients in the chronic post-stroke period. The comparison will be standard care. The main outcome measures are clinically relevant improvement in naming to confrontation, and spontaneous use of the target vocabulary in a connected speech sample (detailed picture description). Secondary outcome includes measured use of the vocabulary in a story-telling, connected speech assessment (retelling of the Cinderella story).

Enrollment

100 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Native English speakers
  • Age 18 years or above
  • Stroke (any type) greater than 12 months post onset
  • No history of neurological disorders / psychiatric disorders
  • Normal or corrected-to-normal hearing & vision
  • Able to give informed consent
  • Currently not receiving Speech & Language therapy
  • Minimal repetition skills (>40% on an immediate word repetition test)
  • Evidence of naming difficulties (<90% in Boston Naming Test - Goodglass et al., 1983)

Exclusion criteria

  • Non-native English speakers
  • Less than 18 years old
  • Stroke less than 12 months post onset
  • History of neurological disorders / psychiatric disorders
  • Uncorrected hearing & vision
  • Unable to give informed consent
  • Currently receiving Speech & Language therapy
  • Insufficient repetition skills (<40% on an immediate word repetition test)
  • Good naming performance (>90% in Boston Naming Test - Goodglass et al., 1983)

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

None (Open label)

100 participants in 2 patient groups

Speeded anomia therapy
Experimental group
Description:
21h of anomia therapy
Treatment:
Behavioral: Speeded anomia therapy
Standard care
No Intervention group
Description:
Participants' typical daily routine

Trial contacts and locations

1

Loading...

Central trial contact

Eleni Zevgolatakou, MSc; Ajay Halai, PhD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems