Sphenopalatine Ganglion Block for Post-Dural Puncture Headache

Wake Forest University (WFU)

Status: Withdrawn

Conditions: Sphenopalatine Ganglion Block; Postdural Puncture Headache

Treatments: Drug: placebo; Drug: bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT02181205

14-024

Details and patient eligibility

About

The investigators are attempting to determine a less invasive method of treatment for postdural puncture headaches that can occur after regional anesthesia. The investigators will be evaluating the relief of headache with those subjects receiving treatment with a sphenopalatine ganglion block with bupivacaine versus placebo, evaluating the incidence of epidural blood patch, pain score of headache at 1 hour, then 24, 48, and 72 hours lower with post study treatment versus placebo, and potential side effects of those patients receiving study therapy as well as epidural blood patch.

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologists assigned class I-III
• age >/= 18 years
• experiencing a postdural puncture headache within 7 days of neuraxial analgesia rated >3/10 pain score

Exclusion criteria

• allergy to study medications <18 years of age pain score on presentation </=3/10 for headache

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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0 participants in 2 patient groups

placebo

Experimental group

Description:

sphenopalatine ganglion block performed with normal saline as the placebo

Treatment:

Drug: placebo

bupivacaine

Active Comparator group

Description:

sphenopalatine ganglion block performed with bupivacaine

Treatment:

Drug: bupivacaine