Spicy Diet on Salty Taste and Salt Intake

Zhiming Zhu

Status: Completed

Conditions: Spicy Diet; Salty Taste

Treatments: Other: No Intervention

Study type: Observational

Funder types: Other

Identifiers

NCT01982669

SATIETY-1

2012CB517805 (Other Grant/Funding Number)

Details and patient eligibility

About

Excess dietary salt intake is closely associated with the development of hypertension and cardiocerebral vascular diseases. Reduction in high salt intake significantly prevents hypertension and cardiocerebral events. Currently, few promising method is available to reduce salt intake in human. This study focus on examining the salty taste in population-level and exploring whether dietary factors can reduce salt intake through acting on salty taste.

Full description

Hypertension and its related complications are common health problems that can lead to multiple organ damage and death. Excessive salt intake plays very important role in the development of hypertension. Reducing salt intake prevents high blood pressure as well as cardiocerebral vascular diseases.

The experimental design is a multi-center, random-order, double-blind observational study to investigate the salty taste and salt intake in population-level.

A total of 606 individuals from four cities in China are recruited in this study. This study aims to explore the salty taste characterization and salt intake in participants who like or dislike spicy diet through questionnaire, spicy preference, salty perception and super-threshold as well as the 24-hour urinary sodium excretion.

Enrollment: 606 patients

Sex: All

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years and ≤ 55 years.
• Willing and able to provide written informed consent.
• Willing and able to comply with all study procedures.

Exclusion criteria

• Hypogeusia or loss due to neural system disease or oral and digestive disease.
• Capsaicin allergy and poor compliance.
• Recently oral diuretics and participate in other pharmacological experiment in 3 months.
• Acute infection, cancer, serious arrhythmias, drug or alcohol abuse.
• Currently have cold, fever, acidosis, dehydration, diarrhea, vomiting during the study.
• Unwilling or unable to communication due to the dysnoesia and language disorders
• Severe neural or psychiatric diseases that would preclude fully understand and corporation in the study.
• Pregnancy or lactation
• Unwilling to sign the informed consent

Trial design

606 participants in 1 patient group

Different degree of spicy food intake

Treatment:

Other: No Intervention