Spinal Anaesthesia for Knee Arthroscopy: Does Lignocaine Shorten the Effect of Bupivacaine

Frederikssunds Hospital, Denmark

Status and phase: Completed; Phase 4

Conditions: Spinal Anesthesia

Treatments: Drug: bupivacaine; Drug: Lidocaine

Study type: Interventional

Funder types: Other

Identifiers

NCT01245868

FRS-AN2009-03-09

Details and patient eligibility

About

The purpose of the study is to investigate if a small amount of lignocaine added to bupivacaine for spinal anesthesia to patients planned for arthroscopic knee surgery, can shorten the duration of the sensoric and the motoric blockade.

Enrollment: 60 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The patient want spinal anaesthesia
• No contradictions against spinal anaesthesia
• Healthy people (ASA-score 1 or 2)
• Body mass index < 35 and between 155 and 190 cm

Exclusion criteria

• Known allergic reactions to planned drugs
• Neurologic disturbances
• Diabetes

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups, including a placebo group

Bupivacaine

Experimental group

Description:

Bupivacaine as used routinely

Treatment:

Drug: bupivacaine

Lidocaine added to bupivacaine

Placebo Comparator group

Description:

lidocaine is added to bupivacaine

Treatment:

Drug: Lidocaine

Drug: bupivacaine