Spinal Bupivacaine/Morphine in Laparoscopic Gastro-intestinal Surgery (Salmon)

Maasstad Hospital

Status: Completed

Conditions: Spinal Bupivacaine/Morphine in Laparoscopic Surgery

Treatments: Drug: Spinal injection bupivacaine/morphine; Drug: subcutaneum injection lidocaine

Study type: Interventional

Funder types: Other

Identifiers

NCT02284282

NL43488.101.13

Details and patient eligibility

About

The objective of this study is to determine if a single spinal shot of morphine can decrease post-operative opioid-use, and thereby decrease opioid side-effects and lead to a quicker recovery after surgery.

Full description

We expect that in laparoscopic gastro-intestinal surgery, a single shot spinal with bupicavaine/morphine will result in a better analgesia in hte first 48 hours. Herby the patients will require less systemic opioids, which will decrease the side-effects. Furthermore, we expect the patients to recover quicker and show an earlier mobilisation and a shorter hospital stay.

The objective of this study is to determine if a single spinal shot of morphine can decrease post-operative opioid-use, and thereby decrease opioid side-effects and lead to a quicker recovery after surgery.

Enrollment: 56 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Laparoscopic Gastro-intestinal surgery

Exclusion criteria

• Bariatric surgery, gastric surgery, rectal surgery, kidney failure, aorta-valve stenosis, coagulation disorders, emergency surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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56 participants in 2 patient groups, including a placebo group

Spinal injection

Active Comparator group

Description:

Patients receive spinal injection Bupivacaine/Morphine

Treatment:

Drug: Spinal injection bupivacaine/morphine

Subcutaneum injection

Placebo Comparator group

Description:

Placebo subcutaneum injections

Treatment:

Drug: subcutaneum injection lidocaine