Spinal Mepivicaine With Fentanyl for Outpatient Knee Arthroscopy

University Health Network, Toronto

Status: Completed

Conditions: Knee Arthroscopy

Treatments: Drug: Mepivacaine with Fentanyl; Drug: Mepivacaine without fentanyl

Study type: Interventional

Funder types: Other

Identifiers

NCT00803725

07-0683-A

Details and patient eligibility

About

The purpose of this study is to determine if the addition of intrathecal fentanyl to low dose mepivacaine spinal anesthesia provides adequate surgical anesthesia with shorter duration of motor blockade.

It is hypothesized that lower doses of spinal mepivacaine when combined with fentanyl will result in adequate surgical block for knee arthroscopy surgery with faster recovery and discharge compared to mepivacaine alone.

Enrollment: 34 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients having unilateral arthroscopic surgery of the knee;
2. ASA I-III status;
3. Age 18-80 years;
4. BMI< 35.

Exclusion criteria

1. Patients who have previous history of hypersensitivity to local anesthetics or contraindications for spinal anesthesia (i.e. bleeding diathesis, coagulopathy);
2. Patients with radiating low back pain and neurological deficits in lower extremities;
3. Patients who are incapable of giving an informed consent.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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34 participants in 2 patient groups

1

Active Comparator group

Description:

Mepivicaine for spinal anesthesia

Treatment:

Drug: Mepivacaine without fentanyl

2

Experimental group

Description:

Mepivacaine with Fentanyl for spinal anesthesia

Treatment:

Drug: Mepivacaine with Fentanyl