Spinal Metastasis as the First Presentation of Lung Malignancy: Clinical Characteristics and Postoperative Survival

Guangdong Provincial People's Hospital (Guangdong Provincial Academy of Medical Sciences)

Status: Completed

Conditions: Lung Cancers; Bone Metastasis

Study type: Observational

Funder types: Other

Identifiers

NCT07100444

lungfirstboneMetas

Details and patient eligibility

About

The aim of this study is to compare the clinical features and postoperative survival outcomes between patients with spinal metastasis as the initial manifestation of malignancy and those with spinal metastasis occurring after an established diagnosis of malignancy.

Full description

The aim of this study is to compare the clinical features and postoperative survival outcomes between patients with spinal metastasis as the initial manifestation of malignancy and those with spinal metastasis occurring after an established diagnosis of malignancy. By analyzing and contrasting these two groups, we seek to identify any distinctive characteristics, prognostic factors, and potential implications for early detection and treatment strategies in patients with malignant spinal metastases.

Enrollment: 139 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age ≥ 18 years.
2. Pathologically or radiologically confirmed diagnosis of lung cancer with spinal metastasis.
3. Patients with spinal metastasis who underwent surgical intervention.
4. Adequate medical records and follow-up data available.

Exclusion criteria

1. Patients with spinal metastasis originating from non-lung primary tumors.
2. Patients who did not receive surgical treatment for spinal metastasis.
3. Incomplete clinical data or lost to follow-up.

Trial design

139 participants in 2 patient groups

Spinal Metastasis as the First Presentation of Lung Malignancy

Description:

It refers to patients who first present with symptoms such as pain or spinal cord compression caused by spinal metastasis, leading to the initial detection of bone metastasis, and are subsequently diagnosed with lung cancer.

lung cancer who subsequently developed spinal metastasis

Description:

It refers to patients with a history of treatment for primary lung cancer who subsequently developed spinal metastasis during the course of the disease.