Splint Versus Steroid Randomized Trial

National University Health System (NUHS)

Status: Unknown

Conditions: De Quervain Syndrome

Treatments: Drug: Hydrocortisone-Lidocaine; Other: Splint

Study type: Interventional

Funder types: Other

Identifiers

NCT05165875

2019/00246

Details and patient eligibility

About

The primary aim is to compare the effectiveness of splinting versus steroid injection in improving the DASH scores in participants diagnosed with De Quervain's tenosynovitis over a period of 6 months.

Full description

The primary hypothesis is that steroid injection into the first dorsal compartment is more effective compared with splinting at 3 months.

The secondary hypothesis is that steroid injection yields better clinical outcomes compared with splinting at 1 month, 3 months and 6 months.

Enrollment: 100 estimated patients

Sex: Female

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Confirmed diagnosis of de Quervain's tenosynovitis based on the de Quervain's screening tool (DQST) with scores ≥ 5 (refer to table 1)
• No prior treatment
• Above 21 years of age

Exclusion criteria

• Allergy to steroid (triamcinolone acetate) or local anaesthetic (lignocaine)
• History of work related trauma

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

Randomized: Steroid injection

Other group

Description:

1ml injection of a mixture of 0.5ml triamcinolone acetonide (50mg/5ml) and 0.5ml 1% lignoacaine is given intra-thecally into the first extensor compartment.

Treatment:

Drug: Hydrocortisone-Lidocaine

Randomized: Splint

Other group

Description:

a long thumb spica thermoplastic splint (wrist neutral, 30º CMCJ flexion, 30º thumb abduction, IPJ free) will be customized and intermittent active range of motion exercises will be taught for 4 weeks

Treatment:

Other: Splint